Issues such as several accounts with similar usernames that differ only in case can be avoided by addressing case sensitivity in the Django's authentication system. Enhancing user experience and security by implementing case-insensitive checks during registration and login helps avoid frequent problems like MultipleObjectsReturned exceptions.

Django project users may find it intimidating to deal with SMTP connection problems, particularly when they get error messages such as WinError 10061, which suggest that the target system has deliberately declined the connection. For mail delivery to be effective, it is essential to configure SMTP settings, such as SMTP backend, port, and TLS usage, correctly.

SMTP configuration errors frequently arise in Django's sturdy framework, making it impossible for messages to be transmitted successfully. In order to improve performance, troubleshooting these issues may require employing asynchronous solutions like Celery, verifying correct authentication, and checking settings.